Flash.Antimicrobial. Macrolides and KetolidesJesus PerezAugust 8, 2023 Welcome to your Flash.Antimicrobial. Macrolides and Ketolides 1. Flashcard#1. Antimicrobial. MacrolidesErythromycin, azithromycin, and clarithromycin are examples of which class of antibiotics?Macrolides. 2. Flashcard#2. Antimicrobial. MacrolidesWhich side effect related to the gastrointestinal system is commonly seen in patients taking macrolides?Gastrointestinal upset, including nausea, vomiting, and diarrhea. 3. Flashcard#3. Antimicrobial. MacrolidesWhat is a significant drug interaction to consider when administering macrolides, especially erythromycin and clarithromycin?They can increase serum levels of drugs metabolized by the liver (CYP450 system), such as warfarin, leading to potential toxicities. 4. Flashcard#4. Antimicrobial. MacrolidesHow should oral forms of macrolides typically be taken in relation to meals?They should be taken with or immediately after a meal to decrease gastrointestinal upset. 5. Flashcard#5. Antimicrobial. MacrolidesWhy should macrolides be used with caution in patients with pre-existing liver disease?Macrolides are metabolized in the liver and can exacerbate hepatic dysfunction. 6. Flashcard#6. Antimicrobial. MacrolidesTelithromycin is classified under which subgroup of antibiotics?Ketolides. 7. Flashcard#7. Antimicrobial. MacrolidesWhich rare but severe side effect has been associated with telithromycin (a ketolide)?Severe liver toxicity, including hepatic failure. 8. Flashcard#8. Antimicrobial. MacrolidesWhy is it essential for nurses to obtain a thorough medication history before administering macrolides or ketolides?To identify potential drug-drug interactions, given the significant impact of macrolides and ketolides on the CYP450 enzyme system. 9. Flashcard#1. Antimicrobial. MacrolidesWhat should a nurse monitor for when administering intravenous forms of macrolides to ensure patient safety?Signs of phlebitis or inflammation at the IV site, as well as monitoring for rapid administration which can cause ototoxicity. 10. Flashcard#10. Antimicrobial. MacrolidesWhy is it crucial for patients to complete the entire course of macrolide or ketolide antibiotics, even if they feel better?To ensure the complete eradication of the bacteria and prevent the development of antibiotic-resistant strains. 1 out of 10 Please fill in the comment box below. Time's up
