Flash. CV. Antilipidemic

Welcome to your Flash. CV. Antilipidemic

Flashcard# 1 CV. Antilipidemic

Why are statins, such as atorvastatin and simvastatin, commonly prescribed?

To lower LDL cholesterol levels and reduce the risk of cardiovascular events like heart attacks and strokes.

Flashcard# 2 CV. Antilipidemic

Which class of antilipidemic drugs is often prescribed to specifically raise HDL cholesterol?

Niacin (nicotinic acid).

Flashcard# 3 CV. Antilipidemic

What is a potential side effect of statins that patients should be educated about and monitored for?

Muscle pain or weakness, which could indicate rhabdomyolysis.

Flashcard# 4 CV. Antilipidemic

Which side effect is commonly associated with niacin therapy and often leads to non-compliance?

Flushing and itching of the skin.

Flashcard# 5 CV. Antilipidemic

Why should grapefruit juice be avoided by patients taking certain statins?

Grapefruit juice can increase serum levels of the statin, leading to enhanced side effects, especially muscle toxicity.

Flashcard# 6 CV. Antilipidemic

Why are fibric acid derivatives (like gemfibrozil) often avoided or used cautiously in patients already on statins?

The combination can increase the risk of muscle toxicity.

Flashcard# 7 CV. Antilipidemic

What baseline assessment is essential before initiating a patient on statin therapy?

Liver function tests, as statins can cause liver enzyme elevations.

Flashcard# 8 CV. Antilipidemic

How should a patient be educated to take a fat-soluble statin for maximum absorption?

It should be taken in the evening with or after a meal, as cholesterol synthesis in the liver is highest during the night.

Flashcard# 9 CV. Antilipidemic

In addition to lipid levels, what should be periodically monitored in patients taking antilipidemic drugs?

Liver function tests, CK (creatinine kinase) for muscle damage, and any symptoms of muscle pain or weakness.

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Flashcard# 10 CV. Antilipidemic

What dietary education is crucial for patients starting on antilipidemic therapy?

Emphasize the importance of a heart-healthy diet, low in saturated and trans fats, along with the medication to optimize cholesterol control.

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