Flash. Endo Bisphosphonate derivatives

Welcome to your Flash. Endo Bisphosphonate derivatives

Flashcard# 1 Endo Bisphosphonate

What is the primary indication for the use of bisphosphonates?

The primary indication is the treatment and prevention of osteoporosis.

Flashcard# 2 Endo Bisphosphonate

What common gastrointestinal side effect is associated with oral bisphosphonates?

Gastroesophageal reflux or heartburn.

Flashcard# 3 Endo Bisphosphonate

Prolonged use of bisphosphonates has been linked to a rare side effect involving the jaw. What is it?

Osteonecrosis of the jaw.

Flashcard# 4 Endo Bisphosphonate

Another rare but severe side effect of bisphosphonates involves which part of the body?

The femur, specifically atypical femur fractures.

Flashcard# 5 Endo Bisphosphonate

Why should patients avoid lying down shortly after taking an oral bisphosphonate?

To prevent esophageal irritation or ulcers.

Flashcard# 6 Endo Bisphosphonate

What is a precautionary measure for patients with renal impairment considering bisphosphonate therapy?

They may need dose adjustments or may be advised to avoid certain bisphosphonates, as these drugs are renally excreted.

Flashcard# 7 Endo Bisphosphonate

When is the best time for a patient to take their oral bisphosphonate medication?

In the morning, on an empty stomach with a full glass of water.

Flashcard# 8 Endo Bisphosphonate

What dietary consideration should patients be aware of when taking bisphosphonates?

They should avoid eating, drinking anything other than water, or taking other medications for at least 30 minutes to 1 hour after administration.

Flashcard# 9 Endo Bisphosphonate

How often are intravenous (IV) bisphosphonates typically administered for osteoporosis?

Typically, once yearly.

10.

Flashcard# 10 Endo Bisphosphonate

What is an important patient teaching point regarding dental work and bisphosphonate therapy?

Patients should undergo a dental examination and complete any necessary dental work prior to starting therapy due to the risk of osteonecrosis of the jaw.

11.

Flashcard# 11 Endo Bisphosphonate

Which vitamin is essential to ensure the efficacy of bisphosphonates?

Vitamin D, along with calcium.

12.

Flashcard# 12 Endo Bisphosphonate

Why should a nurse instruct patients on bisphosphonate therapy to report any thigh or groin pain?

Such pain might be an early indication of a possible atypical femur fracture.

13.

Flashcard# 13 Endo Bisphosphonate

What position should the patient maintain after taking oral bisphosphonates and for how long?

The patient should remain upright (sitting or standing) for at least 30 minutes.

14.

Flashcard# 14 Endo Bisphosphonate

If a patient misses their weekly bisphosphonate dose, what should they do?

They should take the dose the morning after they remember and then return to their original schedule. They shouldn’t take two doses on the same day.

15.

Flashcard# 15 Endo Bisphosphonate

What should a nurse monitor for during intravenous administration of bisphosphonates?

Acute phase reactions like fever, fatigue, and bone pain which can occur within days of the IV dose.

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