Flash. Endo Cortisol-synthesis inhibitorsJesus PerezAugust 3, 2023 Welcome to your Flash. Endo Cortisol-synthesis inhibitors 1. Flashcard#1 Endo Cortisol-synthesis inhibitorsFor what medical condition is the cortisol-synthesis inhibitor ketoconazole commonly prescribed?Ketoconazole is often prescribed for Cushing's syndrome to suppress the overproduction of cortisol. 2. Flashcard#2 Endo Cortisol-synthesis inhibitorsWhich organ system is most at risk for adverse effects when taking cortisol-synthesis inhibitors, especially ketoconazole?The hepatic system; these drugs can cause hepatotoxicity, evidenced by elevated liver enzymes and jaundice. 3. Flashcard#3 Endo Cortisol-synthesis inhibitorsWhy should cortisol-synthesis inhibitors be used with caution in patients with liver disease or those consuming alcohol regularly?These drugs, especially ketoconazole, can cause or exacerbate liver damage. Regular monitoring of liver function tests is essential in these patients. 4. Flashcard#4 Endo Cortisol-synthesis inhibitorsWhen prescribing a cortisol-synthesis inhibitor like metyrapone, what is the key consideration regarding its dosing?Dosing should be titrated based on the patient's 24-hour urinary free cortisol levels and clinical symptomatology to avoid adrenal insufficiency. 5. Flashcard#5 Endo Cortisol-synthesis inhibitorsWhat is the most critical nursing consideration when administering cortisol-synthesis inhibitors to patients?Regularly monitor patients for signs of adrenal insufficiency, such as fatigue, nausea, vomiting, and hypotension, and regularly check liver function tests, especially when using drugs like ketoconazole. 1 out of 5 Please fill in the comment box below. Time's up
