Flash. MS. Anti-gout drugs

Anti-gout medications are primarily used to treat and prevent gout attacks, which are painful inflammations of the joints caused by the accumulation of urate crystals.

Colchicine is often prescribed for acute gout flares due to its ability to reduce inflammation caused by urate crystals.

Potential side effects of allopurinol include rash, kidney impairment, liver enzyme abnormalities, and gastrointestinal upset.

For an acute gout flare, patients are often advised to take a high dose initially, followed by lower doses every hour or few hours until the attack subsides, or until side effects become intolerable.

Patients should be well hydrated to prevent the formation of uric acid kidney stones.

Uricosuric drugs increase the excretion of uric acid in the urine, thereby lowering serum uric acid levels.

Monitoring serum uric acid levels and kidney function is crucial. Additionally, assessing the patient's pain and joint inflammation will determine the effectiveness of the treatment.

Patients should be advised to drink plenty of water, avoid alcohol, and report any signs of rash or hypersensitivity reactions immediately, as these can progress to severe reactions.

Yes, NSAIDs like indomethacin and naproxen are often prescribed for pain relief during acute gout attacks due to their anti-inflammatory effects.

Probenecid can increase the levels of penicillin in the body by decreasing its excretion, potentially leading to increased side effects of penicillin.