Respiratory Pharmacology ExamJesus PerezSeptember 15, 2023 Welcome to your Respiratory Pharmacology Exam 1. Vital signsHealth historyNurses notesHer initial heart rate is recorded at 88 beats/min. Her post-treatment heart rate has increased to 98 beats/min.Question Resp PharmaA 68-year-old woman with a history of moderate persistent asthma presents to the emergency department with shortness of breath. She receives a nebulizer treatment with albuterol. Following the treatment, she informs the nurse that she feels “shaky,” and upon observation, slight tremors of her hands are noted. Based on the patient’s presentation and reaction post-nebulizer treatment, which of the following is the most likely explanation? Please select your answerThe patient is exhibiting an allergic reaction to the medication.These are expected adverse effects of albuterol.The tremors indicate an overdose of albuterol.This reaction is considered an idiosyncratic response to the medication.The patient might have an undiagnosed cardiac condition.The patient is experiencing anxiety or panic. 2. Question Resp PharmaA 52-year-old male with a history of chronic obstructive pulmonary disease (COPD) is seen in the outpatient clinic. He reports increased breathlessness over the past month. His current medications include an inhaled corticosteroid and a long-acting beta-agonist. Given the persistent symptoms, the physician considers adding theophylline to his regimen. During counseling about the medication, the patient inquires about the precautions associated with theophylline use.Which of the following precautions and considerations should be addressed by the nurse when an HCP is prescribing theophylline? Select all that apply Regular monitoring of serum theophylline levels. The potential for interaction with certain foods like chocolate. Increased risk of seizures, especially in overdose. Advising against abrupt discontinuation of the medication. Limited consumption of caffeine-containing beverages. Monitoring liver and kidney function, as they can affect drug metabolism and clearance. 3. Question Resp PharmaA 38-year-old man, recently diagnosed with asthma, visits a respiratory clinic to understand the proper use of his newly prescribed metered-dose inhaler (MDI) containing a short-term beta agonist. During the session, he notices another patient using a spacer with their inhaler and asks the nurse whether he should be using one as well. How should the nurse respond? “Using a spacer helps in delivering more medication directly to the lungs.” “When you use a spacer, the MDI essentially works as a nebulizer.” “Spacers can increase your risk of getting a fungal infection in your mouth.” “It's more challenging to coordinate using an inhaler with a spacer, so it's not advisable.” “Spacers are generally meant for children and not adults.” “The main benefit of a spacer is to reduce the medication's taste and odor.” “Using a spacer requires frequent cleaning, or else it might not work effectively.” 4. Doctor ordersLow-dose inhaled glucocorticoid for daily use.Question Resp PharmaA 14-year-old girl is seen in a pediatric clinic after being diagnosed with mild persistent asthma. Her parents, having done some research on glucocorticoids, share their understanding of the medication with the nurse. Based on their statements, which comment suggests the parents and their daughter might need more clarification about the inhaled glucocorticoid's side effects and precautions? Please select your answer“My daughter might grow a bit slower initially due to the medication, but in the end, she will reach her potential height.”“To maintain healthy bones, she should have adequate calcium and vitamin D intake and engage in consistent exercise.“We are aware that if she uses this inhaler for a long time, she may have an increased risk for glaucoma.”“Using this inhaler will definitely lead to oral thrush and voice changes, but we are prepared for it.”“Our daughter needs to avoid dairy products as they interact with inhaled glucocorticoids.”“It's essential for our child to always rinse her mouth after using the inhaler to reduce the chances of any side effects.”“We are considering additional immunizations because inhaled glucocorticoids weaken the immune system extensively.”“The medication can affect her mood, so we are watching for any signs of depression.” 5. Question Resp PharmaComplete the sentences by choosing from the list of options.A patient with advanced chronic obstructive pulmonary disease (COPD) presenting with symptoms and signs of and has been prescribed a The nurse remains attentive to monitor for potential side effects of the medication. Some known side effects include and If the patient exhibits any of these manifestations, the nurse should recognize them as possibly being linked to the therapy. 6. Question Resp PharmaA 3-month-old infant is admitted to the neonatal intensive care unit (NICU) due to respiratory distress. The medical team starts the baby on high-dose oxygen therapy to ensure adequate oxygenation. The pediatric nurse is discussing the infant's care with a nursing student. The student is asked to identify the potential complications that might arise from prolonged high-dose oxygen therapy in infants. What should the student's response be? Neonatal Osteoporosis. Increased risk of ear infections. Neonatal immune suppression Retinopathy of prematurity. Enhanced cognitive development. Risk of Infantile diabetes. Gastroesophageal reflux in newborn Accelerated teething process. 7. Medication listTerbutaline 0.25 mg q15-30min x 3 doses PRN in lateral deltoidNot to exceed 0.5 mg/4 hrQuestion Resp PharmaA 55-year-old woman is admitted to the respiratory unit with a diagnosis of bronchitis. Aware of certain contraindications associated with the prescribed medication, the nurse reviews the patient's medical history. Which of the following two parameters would raise concern when using this medication? Hand deformities High Blood pressure Low hemoglobin count Low bone density Low thyroid levels High intraocular pressure High blood glucose High plasmatic uric acid 8. Question Resp PharmaA 29-year-old male has been newly diagnosed with asthma after experiencing recurrent episodes of wheezing and shortness of breath. His primary care provider is starting him on zafirlukast, a leukotriene receptor antagonist (LTRA). The patient is keen on understanding how the medication works and when he should take it. He also wants to know about any potential side effects. As the nurse in charge of his education, which of the following two statements would be most appropriate to explain to the patient about his new medication? "You should expect to feel better immediately after starting this medication." "Take the medication only when you feel a severe asthma attack coming on." "Zafirlukast primarily acts by reducing the inflammation in your lungs, which in turn helps prevent asthma attacks." "Always keep this medication handy and take a dose before any physical activity." "The most common side effect of this drug is constipation, so you might want to consider increasing fiber and fluid in your diet." "This medication can take some time before you see its full benefits, often about 3 to 4 weeks." "If you forget a dose, just double up on the next one." "You should only take this medication once every other day." 9. Question Resp PharmaA 54-year-old man with a history of chronic bronchitis is being discharged from the hospital. As part of his management plan, he has been prescribed the anticholinergic inhaler ipratropium bromide to help reduce his bronchospasm. The nurse has been educating him about the proper use and expectations of the medication. At the end of the session, which statement by the patient would indicate to the nurse that he has understood the instructions related to ipratropium bromide? "I've been told to increase my fruit intake, so I'll have grapefruit juice every morning with this medication." "I'll probably need a new wardrobe with all the weight I'll gain from this inhaler." "If I suddenly have difficulty breathing, I'll use this inhaler immediately as my only relief." "It's quite common to feel very nauseous or even vomit after using this inhaler, isn't it?" "I'll keep this inhaler with me at all times, especially during exercise." "This inhaler isn't the one I should rely on if I have a sudden asthma attack." "I should keep a watch on my blood sugar levels since this medication will likely increase it." 10. Question Resp PharmaA client has been taking rifampin and isoniazid for the treatment of active tuberculosis. Which side effects does the nurse anticipate the client may experience while taking the medication? Select all that apply. Red-orange color to urine Pain in the joints Constipation Blurry vision Yellowing of the sclera Sunburn and photosensitivity Nausea Disturbed visual color discrimination Peripheral neuropathy 11. Question Resp PharmaA 72-year-old male patient with a history of chronic obstructive pulmonary disease (COPD) has been hospitalized due to an acute exacerbation. As he prepares for discharge, he is provided with prescriptions for both albuterol and salmeterol to manage his COPD symptoms. During discharge education, the nurse explains the proper use of both inhalers. When evaluating the patient's understanding of the education, which statement made by the patient suggests a need for further teaching? “Before using the inhaler, I'll insert it into the spacer and give it a good shake a few times.” “If I suddenly feel like I can't breathe, I'll immediately use the salmeterol.” “After taking a puff from my inhaler, I'll wait a minute before taking the second puff.” “It's a good practice to check my heart rate before and after using my bronchodilator.” “I'll use albuterol as my daily maintenance inhaler.” “If I forget a dose of salmeterol, I'll double the dose the next time.” “I will clean my inhalers every week to make sure they work effectively.” 12. Question Resp PharmaA 67-year-old male with a smoking history of 40 pack-years is admitted to the emergency room with exacerbation of chronic respiratory symptoms. His oxygen saturation is 90% on room air, and the resident doctor is considering placing him on supplemental oxygen. The head nurse is concerned about using a high concentration of oxygen in this patient, given his likely underlying medical condition.What is the primary reason to avoid high oxygen concentrations in patients like him? Please select your answerIt can lead to fluid overload.It can suppress the respiratory drive leading to hypercapnia.High oxygen levels can cause pulmonary fibrosis.Oxygen can increase the risk of pulmonary embolism.High oxygen concentrations can lead to oxygen toxicity.It can exacerbate underlying lung infections.High oxygen levels can increase blood pressure significantly.It may increase the risk of lung cancer. 13. Physician orderOrder: Special Lab: Cycloserine Level next week.Question Resp PharmaA 38-year-old alcoholic woman has recently been diagnosed with tuberculosis and started on a regimen that includes cycloserine, administered orally twice daily. At her follow-up appointment a week later, the nurse informed her that she would need to have blood drawn to assess the serum concentration of the medication. The patient appears anxious about the upcoming procedure. The nurse provides instructions about medication administration in relation to the test.Which of the following is the most appropriate guidance? Withhold the morning dose on the day of the scheduled blood test. Take the morning dose, and have the blood drawn 2 hours after taking the dose. Withhold the evening dose before the test and the dose scheduled for the morning of the test. Double the dose the evening before the test, and withhold the morning dose on the day of the test. Take the medication as usual, no special instructions needed. Split the morning dose into two and take half before and half after the test. Withhold the morning dose and take it immediately after the blood test. Double the morning dose on the day of the test after the blood is drawn. 14. Question Resp PharmaA 45-year-old man with a history of chronic bronchitis has recently been prescribed a methylxanthine bronchodilator to help manage his respiratory symptoms. During the client education session, the nurse discusses potential drug interactions and dietary considerations.Which of the following beverages would the nurse advise the client to avoid while taking this medication? Please select your answerOrange juice.Herbal tea.Carbonated water.Coffee.Green tea.Apple juice.Cranberry juice.Chocolate milk. 15. Question Resp PharmaA 46-year-old man with a history of asthma presents to the primary care clinic for a routine follow-up. The nurse notes that the patient has been prescribed both pirbuterol and beclomethasone dipropionate via metered-dose inhalers. The patient is unsure about the correct sequence in which to use these medications. The nurse aims to instruct the patient on the best practices to ensure the effectiveness of both drugs. How should the nurse guide the patient in administering these medications? Instruct the patient to take pirbuterol first, wait a few minutes, and then take beclomethasone. Recommend alternating a single puff of pirbuterol with beclomethasone, ensuring beclomethasone is taken first. Suggest the patient to take both pirbuterol and beclomethasone together without any intervals. Advise taking pirbuterol, waiting for about 30 minutes, and then administering beclomethasone. Propose the use of pirbuterol in the morning and beclomethasone in the evening. Instruct the patient to use beclomethasone first, followed immediately by pirbuterol. Recommend alternating a single puff of beclomethasone with pirbuterol, beginning with pirbuterol. Suggest the use of pirbuterol only during asthma attacks and beclomethasone for daily maintenance. 16. Question Resp PharmaA young couple with a 20-month-old toddler visits a community health clinic.Parents express concern about their child's frequent sneezing and watery eyes, especially after playing outside. They believe these symptoms might be related to allergies and are considering using an over-the-counter (OTC) allergy medication they saw at the local pharmacy. As a nurse, you want to provide them with general education on the use of OTC allergy medications for children.What instructions should be appropriate and which ones not in order to teach the parents?AppropriateNot appropriate"It's best to give the OTC allergy medication just before your toddler goes outside to play." "Always discontinue the OTC allergy medication at least 2 days before any planned allergy testing." "The OTC allergy medication can cause side effects like dry mouth and difficulty urinating, so always monitor your child after giving any dose." "It's okay to use the OTC allergy medication as often as needed, as long as it helps with the symptoms." "While the OTC allergy medication may help alleviate signs and symptoms, remember it's not a permanent cure for allergies." "Always consult with a pediatrician before giving any OTC medication to children younger than 2 years of age." "If you notice any rash or unusual behavior in your toddler after giving the medication, discontinue its use immediately and seek medical advice." "You can combine the OTC allergy medication with other children's medicines for better effect." 17. Question Resp PharmaA 68-year-old female patient is in the intensive care unit following a severe respiratory failure. She is intubated and on mechanical ventilation. The nurse observes a buildup of secretions in the endotracheal (ET) tube and prepares to suction it out. A nursing student is observing the procedure. After the nurse completes the suctioning, the student is asked to describe the correct procedure for suctioning through an endotracheal tube. Which of the following statements by the nursing student indicates a correct understanding of the procedure? "The suction catheter is always inserted through the nose first to clear the upper airway, and then through the ET tube to suction the lower airway." "While continuous suction is maintained, the catheter is inserted into the ET tube, and once resistance is felt, the catheter is slowly removed." "The catheter is introduced into the ET tube, and intermittent suction is done until no more secretions can be seen; the catheter is then taken out." "The suction catheter should be pushed into the ET tube until some resistance is felt, and then intermittent suction should be applied as it's being pulled out." "The suction catheter is inserted into the ET tube and left there until all the secretions are cleared without any intermittent suctioning." "The catheter should be inserted fully into the ET tube, left there for a minute, and then pulled out without any suctioning." "The suction catheter is inserted halfway into the ET tube, and then suction is continuously applied while slowly withdrawing the catheter." 18. Question Resp PharmaA 55-year-old woman presents to the outpatient clinic complaining of intermittent sneezing, itchy eyes, and nasal congestion, suggestive of allergic rhinitis. The physician recommends a first-generation H1 antihistamine for symptom relief. The patient is a school bus driver and asks about any potential side effects or precautions she should be aware of, given her profession. The nurse begins counseling her on the implications of taking first-generation H1 antihistamines. Which statement by the nurse would be most accurate? “These medications are generally side-effect free and safe for everyone.” “First-generation antihistamines can cause drowsiness and impair your ability to drive.” “You should drink alcohol when taking this medication to enhance its effectiveness.” “These drugs increase alertness, so you won't feel tired during your job.” “First-generation antihistamines are known to increase blood pressure significantly.” “You should expect an improvement in memory and cognitive function when on this medication.” “This medication will act as a decongestant and improve your breathing.” 19. Nurses notesGiven his recurrent episodes of thick sputum production, the healthcare provider has prescribed a mucolytic enzyme to assist in clearing the secretions. He is also on a bronchodilator to help with his breathing difficulties.Question Resp PharmaA 54-year-old male with a history of chronic bronchitis visits the outpatient clinic for his routine follow-up.As the nurse is reviewing his medications, the patient is unsure about the timing of administering the two inhalers. How should the nurse guide the patient in terms of the sequence and timing of using these medications? "You should take the bronchodilator first, wait for about 5 minutes, and then use the mucolytic enzyme inhaler." "Use the mucolytic enzyme inhaler first, and then immediately take the bronchodilator." "It doesn't matter which one you use first; you can use them simultaneously." "You should space out the two inhalers by at least an hour, starting with the mucolytic enzyme." "Use the mucolytic enzyme in the morning and the bronchodilator in the evening." "You should alternate days of use: bronchodilator one day and mucolytic enzyme the next." "Use the bronchodilator whenever you feel breathless and use the mucolytic enzyme only when you feel there's a lot of phlegm." 20. Question Resp PharmaA 66-year-old female with a history of chronic obstructive pulmonary disease (COPD) presents to the emergency department with worsening cough and shortness of breath. She reports taking multiple over-the-counter medications to manage her persistent cough, including an antitussive containing codeine that she started 2 days ago. The healthcare team is concerned about her use of codeine in the context of her respiratory history. Why is caution advised when using antitussives with codeine in patients like her, who have respiratory insufficiency? Codeine increases the production of mucus, worsening respiratory function. Codeine can lead to a rapid drop in blood pressure, exacerbating symptoms of respiratory insufficiency. Codeine may suppress the respiratory drive, posing a risk of respiratory arrest in those with compromised lung function. Codeine counteracts the effects of other medications prescribed for respiratory insufficiency. The metabolic byproducts of codeine can further irritate the lungs, leading to increased coughing. Codeine can cause an allergic reaction that manifests as bronchospasm. Use of codeine can lead to excessive drowsiness, masking the worsening of respiratory symptoms. 21. Question Resp PharmaA 58-year-old male with a history of chronic heart failure is admitted to the medical unit with acute shortness of breath. The healthcare team is evaluating appropriate oxygen delivery methods to optimize his oxygenation. The team is deliberating between a nonrebreathing mask and a Venturi mask for this patient. As a nurse on the team, you're asked about the primary differences between these two oxygen delivery devices. Which of the following statements best differentiates a nonrebreathing mask from a Venturi mask? nonrebreathing mask Venturi mask Venturi mask nonrebreathing mask Venturi mask nonrebreathing mask utilizes air entrainment to mix room air with pure oxygen delivers high-flow oxygen Delivers a variable oxygen concentration delivers low-flow oxygen. is primarily used for patients with chronic conditions Uses a reservoir bag to collect the oxygen 22. Question Resp PharmaA 47-year-old female patient with severe persistent asthma not well-controlled on high-dose inhaled corticosteroids and long-acting beta-agonists is started on omalizumab therapy. On her follow-up visit after 3 months of treatment, she reported some new symptoms. The nurse knows that some of these might be potential side effects of omalizumab. Which of the following three symptoms are commonly associated with omalizumab? Diarrhea and stomach cramps Joint pain and muscle aches Vision changes and dizziness Frequent episodes of hiccups Skin rash and hives Persistent dry cough Reduced sense of taste Leg swelling and shortness of breath 23. Question Resp PharmaA 56-year-old male, admitted to the respiratory ward due to an exacerbation of his chronic obstructive pulmonary disease (COPD), has been receiving theophylline intravenously to help manage his symptoms. The attending pulmonologist has decided to transition the patient to an oral form of the medication and has prescribed an immediate-release version. The nursing team is responsible for ensuring a seamless transition from IV to oral medication. When should the nurse administer the first dose of the oral theophylline to the patient? Just after the next meal. Just before the next meal. 4 hours after discontinuing the IV form. Immediately upon discontinuing the IV form. 2 hours after discontinuing the IV form. 6 hours after discontinuing the IV form. After the next vital sign check. At the patient's regular bedtime. 24. Question Resp PharmaA 32-year-old woman presents to the outpatient clinic with a history of recurrent wheezing, coughing, and shortness of breath, especially during the spring months. She has been diagnosed with allergic asthma and has been prescribed cromolyn sodium as part of her treatment regimen. The nurse, while explaining the mechanism of the medication, mentions its primary therapeutic goal for patients with allergic asthma.What is the primary goal of administering cromolyn sodium in the management of allergic asthma? To dilate the bronchial airways. To suppress the inflammatory response. To reduce mucus production in the airways. To provide immediate relief from acute bronchospasm. To replace corticosteroids in the treatment plan. To act as an antihistamine and prevent allergic reactions. To increase the strength of respiratory muscles. To suppress the cough reflex. 25. Question Resp PharmaA 42-year-old man is seen at the outpatient pulmonary clinic with symptoms consistent with bronchial asthma. As part of his management, the physician considers prescribing Zafirlukast. The nurse knows that before initiating this medication, a particular laboratory test is often ordered to assess potential risks. Which of the following laboratory tests is typically ordered before administering Zafirlukast? Complete Blood Count (CBC). Thyroid Function Tests. Serum electrolytes. Blood glucose level. Liver function tests. Blood urea nitrogen (BUN) and creatinine. Arterial blood gases. Coagulation profile. 26. Question Resp PharmaA 59-year-old male with a history of moderate to severe plaque psoriasis has been recommended to start monoclonal antibody therapy. During the assessment, the nurse reviews the patient's past medical history. Given the potential risks associated with monoclonal therapy, it's important for the nurse to determine if the patient has a history of any pre-existing infections. Which of the following infections would be a concern prior to initiating monoclonal antibody therapy?The infections of concern will be and 27. Question Resp PharmaA 42-year-old female presents to the outpatient respiratory clinic with complaints of increasing shortness of breath and a persistent cough over the past 6 months. Her pulmonary function tests suggest obstructive lung disease. The pulmonologist discusses various medication options for managing her symptoms. The nurse is tasked with educating the patient on the characteristics of each medication.Match the following respiratory medications with their most unique and important characteristics: Albuterol Fluticasone Ipratropium bromide Theophylline Montelukast Xanthine derivative that requires serum level monitoring due to its narrow therapeutic index. Leukotriene receptor antagonist used as a controller medication for asthma. Short-acting beta2-adrenergic agonist (SABA) used for acute bronchospasm relief. Long-acting anticholinergic bronchodilator primarily used for COPD. Inhaled corticosteroid (ICS) used for long-term control and prevention of asthma symptoms. 28. Medication orderRevefenacin 175 mcg inhaled PO qDay via nebulizer using a mouthpieceAdminister at the same time every dayNot to exceed 175 mg once dailyQuestion Resp PharmaMrs. Jenny a 57-year-old female with a history of chronic obstructive pulmonary disease (COPD) has been prescribed revefenacin by her primary care physician. During her nursing consultation, she expresses uncertainty about the medication and asks for further guidance. The nurse decides to highlight the essential precautions associated with revefenacin.Which of the following precautions should the nurse prioritize when discussing the use of revefenacin with the patient? Select all that apply Be vigilant for signs of paradoxical bronchospasm; discontinue the medication and seek medical help if you experience sudden worsening of breathing after use. Always rinse your mouth after inhaling the medication to reduce the risk of oral infections. Exercise caution when driving or operating machinery, as revefenacin may lead to blurred vision. Inform your healthcare provider if you have a history of benign prostatic hyperplasia (BPH) or other urinary issues, as the medication can cause urinary retention. Make sure to use the medication outdoors to avoid any indoor pollution. Revefenacin can be used as a first-line treatment for pneumonia. Store the medication in a fridge to prolong its shelf life. It's acceptable to mix revefenacin with other inhalation solutions. 29. Question Resp PharmaA 3-day-old preterm infant is admitted to the neonatal intensive care unit (NICU) with signs of respiratory distress syndrome (RDS). The pediatrician has ordered the administration of poractant alfa as part of the treatment plan. The nurse, aware of the specific considerations associated with the drug, prepares for the administration.What are the key nursing implications the nurse should consider when administering poractant alfa to this infant? Select all that apply Ensure the infant's airway is patent and the infant is adequately ventilated before administration. Store any unused portions of the medication for future doses. Administer the medication quickly to avoid settling of the suspension. Monitor the infant for potential complications such as bradycardia, oxygen desaturation, or reflux of the medication into the endotracheal tube. Regularly assess the infant’s lung sounds and respiratory status after administration to ensure the medication is improving lung function. Avoid oral feeding of the infant immediately before or after the administration. Administer via intravenous (IV) route to ensure rapid onset of action. 30. Question Resp PharmaA 56-year-old woman with a known history of asthma presents to the emergency department after using her prescribed bronchodilator inhaler. Instead of the expected relief, she complains of worsening shortness of breath and tightness in her chest immediately after the inhalation. Complete the diagram below by dragging from the choice below what condition the client is most likely experiencing, two actions the nurse would take to address that condition, and two parameters to monitor to assess the client's condition. Nursing InterventionsReassure the patientImmediately discontinue the bronchodilatorAdvise her to continue using the inhaler.Administer propranolol as prescribed.Prepare for the administration of an alternative bronchodilator Most likely conditionSubcutaneous emphysemaRefractory asthmaParadoxical bronchospasmAsthmatic status Parameters to monitorUrinary output.Breath soundsRespiratory rateOxygen saturation levelsHeart rate